Gentile da Fabriano was born in Fabriano in 1370.

Representative of the International Gothic painter of rich culture, mainly Flemish and Lombard.

His early works, including the Polyptych of Valle Romita, present the typical features of his painting: rich draperies, linearity contours, splendor of the costumes, all the typical elements of the International Gothic style.

The first safe chronological data goes back to 1408 when the painter was in Venice, where he painted a fresco in the Palazzo Ducale then lost.

From 1414 to 1419 he was in Brescia, then probably in Fabriano and Siena; in Florence in 1422 he executed for Palla Strozzi Chapel of the Holy Trinity in the famous Adoration of the Magi who is now in the Uffizi in Florence. This painting has survived intact in its frame carved and painted in gold, the characters of the scene, wearing rich costumes, are immersed in a fairy-tale atmosphere almost unreal but combined with a careful description veristic of plants and flowers.

In 1425 he painted, also in Florence, the Polyptych Quaratesi today divided between London, Florence, Vatican and Washington; In the same year the artist was in Siena, then to Orvieto where he painted the frescoes in the cathedral.

In 1427 is located in Rome, where he began in the basilica of St. John Lateran in a cycle of frescoes that were destroyed by the seventeenth-century reconstruction of the church.
Gentile da Fabriano died in Rome in 1427.